Supported by the state-of-the-art cGMP facilities and combined strategies for peptide synthesis, we are flexible in peptide synthesis capacity from milligram scale of non-cGMP batches to kilogram scale of cGMP batches.

 

Major peptide technologies include:

 

Solid Phase Peptide Synthesis(SPPS)

SPPS technology is commonly applied for longer and more complex sequences, and is usually used to manufacture large scale of peptide APIs. The batch size reaches kilograms.

 

◆ Solution Phase Synthesis(SPS)

SPS technology is particular applied for shorter peptide sequences.

 

◆ Combined synthesis strategies for upscaling

In some occasions, we may use SPS technology to synthesis small peptide fragments, and then use SPPS technology to make these small fragments conjunct to form longer peptides. For some longer peptides, this methods is often used and it’s an economic way of upscaling the manufacturing process and time-saving.

 

◆ Purification

An optimal purification strategy is vital to guarantee the product’s purity and related substances. SINOPEP offers the latest techniques to secure product purity and identity in conformance with customer specifications: preparative HPLC, conventional chromatography, ion exchange, gel chromatography, counter-current distribution and etc.

   

◆ Lyophilization

For the final isolation stage, SINOPEP can offer flexible lyophilization technologies according to customer’s requirements.

  • Peptides
  • Generic APIs
  • Custom Peptide Synthesis